Job Introduction
We are looking for:
Director/ Senior Director - DMPK
At Pharmaron we offer:
- Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!
- Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!
- A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!
Requirements:
- PhD or equivalent experience in relevant scientific discipline, pharmacology, pharmaceutical sciences.
- Multi-year experience working in DMPK drug discovery and development projects with a track record of delivery.
- In depth understanding of DMPK science with additional knowledge of related disciplines.
- Experience of working within matrix teams.
- Expertise in problem solving across DMPK/ADME applied to drug discovery.
- Experience in PK, PKPD or PBPK modelling would be advantageous.
Key roles and responsibilities:
- As the frontline DMPK discipline contact, provide leadership, design and successful delivery of DMPK, PKPD, modelling and progression strategies for multiple small molecule drug discovery projects from hit-finding through to candidate selection.
- Work collaboratively internally as part of cross discipline matrix teams and with our client partners in the design, identification and optimisation of candidate molecules.
- Presentation of plans, strategy and achievements to external partners and internal stakeholders including local and global senior management.
- Assist in the procurement of new business through provision of strategic DMPK requirements to new business proposals
- Ensure delivery of project goals through interpretation of results and integration of data with other disciplines. This includes, but is not limited to optimisation of ADME and PK properties, DDI assessments, formulation recommendations, PKPD and PBPK modelling.
- Ensure robust estimations of human PK and dose prediction from early in a project lifecycle through to candidate nomination to guide project direction and clinical potential.
- Provide disciplinary scientific leadership and expert technical direction across the department and apply innovation to problem solving and enhancement to DMPK services within Pharmaron.
- Supervision or mentoring of other DMPK colleagues
Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.
We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.
Pharmaron acquired the Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference area in February 2017. The research building has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery teams. In addition, a Formulation Development team was also recently established. The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), Formulation Development (FD) and Process Chemistry (PC).
- We offer a competitive salary and a progressive and comprehensive suite of employee benefits.
- We offer state of the art working environment on site.
- We offer the opportunity for growth and development and will support funding for relevant training and development programmes.
Why Should You Apply?
- This is an opportunity for you as a Director/ Senior Director - DMPK professional to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition and the desire to grow with the department.
- Build and shape your career in an environment that sets and commits to the highest standards.
- To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.
Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development. With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan, and China.