Downstream Development Scientist

Job Introduction

We are looking for:
  
 A Downstream Process Development Scientist to deliver and lead a wide range of activities associated with the design, development, scale-up, technical transfer and validation of cGMP clinical manufacture of bulk drug substances across the Process Development Laboratories and Production areas.   

At Pharmaron we offer:

• Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!
• Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!
• A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!

Requirements:

• PhD (or equivalent industrial experience) in relevant life sciences or process engineering field
• Proven industrial experience within the field of bioprocess development, scale-up, cGMP manufacturing or process and equipment qualification and validation
• Experience of taking responsibility for leading some activities within the design and delivery of projects
• Evidence of ability to effectively influence to multi-disciplinary scientific teams
• Proven industry experience in mammalian, microbial or viral based processes
• Knowledge and experience in the use of statistical techniques for the planning and analysis of experiment

Key roles and responsibilities:

•  Set exemplary standards within the laboratory and facility in compliance with Development, Quality and EHS Policies and Procedures.
• Support Project leads on delivery of both internal and client-based work packages.
• The planning, design, delivery and reporting of activities within the laboratory, pilot plant and/or production facility to meet project timelines in line with policies and procedures.
• The preparation and execution of a range of documentation including but not limited to operating procedures, manufacturing records and validation protocols in a timely manner with a right first-time mind set.
• Drive 5S and operational excellence initiatives as a means for continuous improvement to ensure that department the department is a high performing team.
• Lead on the delivery of new capital equipment items and train others in procedures/techniques, equipment and technologies to increase Biologics Development capabilities.
• Analyse any investigation data to a high standard and ensure that protocols and procedures are delivered with a high attention to detail
• Complete all laboratory or batch related documentation in a timely and compliant manner, participating in reviews of the documentation to obtain quality sign off when necessary
• Subject matter expert in areas relating to GMP manufacture, upstream process development, downstream process development or cell line development
• Provide periodic cover outside of normal working hours for essential operations when required by the business. 
• Perform all activities in accordance with regulatory, quality and EHS requirements.
• Expand expertise in areas relating to GMP manufacture, support, upstream process development, downstream process development or cell line development        

Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.

We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.

We are based in the vibrant city of Liverpool with a world class R&D and manufacturing facility that offers a complete end to end development service. Our 80,000 sq. ft facility houses an established Biologics Department that consists of Analytical and Process Sciences. Our Liverpool site has a remarkable 20 Year Track Record in Biologics Development, which now offer A Fully Integrated

Gene Therapy Drug Substance Solution in our state of the art cGMP facility purpose designed for viral vectors with onsite plasmid DNA and renowned analytical capabilities for release and characterisation

The Pharmaron Liverpool Team has consistently delivered biologics programs across all development phases and due to constant growth we are now recruiting a Downstream Development Scientist.

• We offer a competitive salary and a progressive and comprehensive suite of employee benefits
• We offer state of the art working environment in our modern Liverpool site
• We offer the opportunity for growth and development and will support funding for relevant training and development programmes

We do more than manufacture batches, we develop medicines!

Why Should You Apply?

• This is an opportunity for you as a Downstream Development Scientist professional to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition and the desire to grow with the department.
• Build and shape your career in an environment that sets and commits to the highest standards.
• To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.

Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development.  With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan, and China.