Job Introduction
We are looking for:
Experienced Computational Chemist-Drug Discovery
At Pharmaron we offer:
- Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!
- Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!
- A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!
Requirements:
- PhD in chemistry or closely related discipline eg. Computational physical or theoretical chemistry or structural biology
- Multi-year experience in world class small molecule drug discovery organization(s)
- Structure and ligand-based drug discovery
- Scripting and/or pipelining tools
- Combine above to contribute to drug discovery
- Strong familiarity with a wide range of current computational chemistry software
- Decide and communicate scientific/tactical choices
- Presentation skills
- Decide and communicate scientific/tactical choices
- Excellent motivation and team building skills
- Analytical and Problem solving skills
- Excellent interpersonal skills
- Excellent organization skills, focused on execution, with strong attention to detail
- IT skills with a good working knowledge of MS Office
- Able to work across geographies and cultures
Key roles and responsibilities:
- Support and drive small molecule drug discovery projects from hit-finding, through lead generation and lead optimization to candidate selection, utilizing in-house resources and jointly with Pharmaron partner organisations.
- Through scientific leadership and collaboration with colleagues, provide clear data analyses, actionable hypotheses and ideas to steer overall project and, in particular, medicinal and synthetic chemistry project contributions.
- Ensure:
- Present plans, tactics and achievements to external partners and to internal stakeholders including project and Senior Management.
- Provide flexible support to the scientific and operational needs of the department.
- Be willing to develop new skills and assume responsibility for new capabilities.
- the candidate will creatively and proactively apply computational methods, including structure-based drug design,
- homology modeling,
- conformational analysis, docking, virtual screening, molecular dynamics, quantum methods, cheminformatics, diversity/similarity analysis
- QSAR/machine learning/artificial intelligence to the analysis of project data and design of project compounds to advance multiple drug discovery projects.
Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.
We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.
Pharmaron acquired the Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference area in February 2017. The research building has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery teams. In addition, a Formulation Development team was also recently established. The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), Formulation Development (FD) and Process Chemistry (PC).
- We offer a competitive salary and a progressive and comprehensive suite of employee benefits.
- We offer state of the art working environment on site.
- We offer the opportunity for growth and development and will support funding for relevant training and development programmes.
Why Should You Apply?
- This is an opportunity for you as Experienced Computational Chemist professional to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition and the desire to grow with the department.
- Build and shape your career in an environment that sets and commits to the highest standards.
- To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.
Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development. With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan, and China.