Please Note: The application deadline for this job has now passed.
Job Introduction
We are looking for:
We have opened a new Bioanalysis group at the Hoddesdon site to complement our work at Rushden. This team will work closely with the newly formed in vitro DMPK Assay group at Hoddesdon.
The Pharmaron Team is looking to expand and recruit a Discovery Bioanalysis Senior Scientist / Technical Specialist with strong experience of developing LC-MS methods for the quantitative measurement of small molecules.
At Pharmaron we offer:
- Vibrant and dynamic employment – we are a highly specialised, growth company operating in a critical sector of the economy – our future is strong and exciting!
- Opportunities to develop your skills and yourself – our rapid growth brings greater opportunities for you to learn and grow faster!
- A great team where we all support each other – enjoy your work – after all you spend about a third of your time here!
Requirements:
- PhD, MSc or BSc (Hons) in Chemistry or related subject
- Demonstrated experience with small and/or large molecule LC-MS method development, validation and troubleshooting in a CRO or Pharmaceutical Company.
- Extensive experience of quantitative triple quadrupole mass spectrometry (Sciex triple quadrupole platforms) paired with liquid chromatography (e.g., Agilent systems)
- Extensive experience in the development of sample extraction and work-up methods. Experience of automation platforms (e.g., Hamilton, Tecan) advantageous
- Proficient in the use of relevant software e.g., Analyst, Watson, WinNonLin.
- Good understanding of the regulated bioanalysis guidelines.
- Understanding of the drug development process.
- Scientific data interpretation, reporting and presentation skills.
- Coaching & Mentoring.
Key roles and responsibilities:
- Developing bioanalytical LC-MS methods for small and large molecules in discovery phase studies with rapid turnaround times, for subsequent assay qualification and sample analysis.
- Act as study supervisor on discovery phase studies
- Provide analytical support for in vitro DMPK assays with rapid turnaround times.
- Providing analytical trouble shooting support as required.
- Training and mentoring less experienced staff in method development and operation of mass spectrometers.
- Ensuring work is conducted, documented, and reported in line with department practices and governing policies, and with client requirements where appropriate.
- Identifying new technologies, which could be of significant benefit to the group, improving capability or reducing operational costs.
- Increasing the profile of the department externally through playing an active role in expert groups, networking, and publications.
Our Company: “We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world’s leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges”.
We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.
Pharmaron acquired the Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference area in February 2017. The research building has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery teams. In addition, a Formulation Development team was also recently established. The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), Formulation Development (FD) and Process Chemistry (PC).
- We offer a competitive salary and a progressive and comprehensive suite of employee benefits.
- We offer state of the art working environment on site.
- We offer the opportunity for growth and development and will support funding for relevant training and development programmes.
Why Should You Apply?
- This is an opportunity for you as a LC-MS Bioanalytical professional to make a real impact in a highly scientific and regulated environment, demonstrate leadership, ambition and the desire to grow with the department.
- Build and shape your career in an environment that sets and commits to the highest standards.
- To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.
Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal, and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development. With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan, and China.