Job Introduction
Technical Specialist, Metabolite Identification & LC-MS
Location: Rushden, UK
About Pharmaron
Pharmaron is a global contract research and manufacturing organisation supporting pharmaceutical and biotechnology companies from early discovery through clinical development and manufacturing.
With more than 29,000 employees across 28 locations in the UK, US, China and Singapore, we provide integrated services across small molecules, biologics, antibody-drug conjugates and gene therapies.
Last year, our teams supported 887 discovery projects, more than 1,100 CMC programmes and 1,397 clinical trials across all phases, working with more than 3,300 customers globally.
To learn more, visit www.pharmaron.com.
About the Role
We are seeking a Technical Specialist, Metabolite Identification & LC-MS to join our Metabolism team in Rushden.
This is a scientific position for an established scientist with strong expertise in metabolite identification, high-resolution mass spectrometry, structure elucidation and LC-MS/MS data interpretation.
You will act as a technical expert, applying your scientific judgement to complex regulatory and non-regulatory studies across in vitro, in vivo, clinical, biological and environmental fate programmes.
Working closely with Study Directors, Analytical Project Managers and clients, you will provide scientific direction, develop analytical strategies, interpret complex datasets and support the successful delivery of customer programmes. You will also contribute to the development of new technical capabilities.
This position would suit a Scientist who wants to broaden their scientific knowledge while remaining closely involved with laboratory science and data interpretation.
Key Responsibilities
- Act as a subject-matter expert in metabolite identification, metabolic profiling and structure elucidation using HRMS.
- Apply knowledge of Phase I and Phase II metabolism across regulatory and non-regulatory studies to interpret accurate-mass and MS/MS data to identify metabolites, fragmentation patterns and biotransformation pathways.
- Develop, optimise and troubleshoot LC-MS/MS methods.
- Work with Study Directors and Analytical Project Managers to deliver projects and resolve technical challenges.
Candidate Profile
- Significant hands-on experience in metabolite identification, biotransformation, DMPK or a related HRMS field.
- PhD, MSc or BSc in chemistry, analytical chemistry, biochemistry, pharmaceutical science or a related discipline.
- Strong LC-MS/MS method development, optimisation and troubleshooting skills.
- Demonstrable experience interpreting accurate-mass and MS/MS fragmentation data and proposing metabolite structures.
- Strong knowledge of Phase I and Phase II metabolism and biotransformation pathways.
- Strong scientific reporting, presentation and client communication skills.
- Strong project management, problem-solving and prioritisation skills.
- A meticulous approach to laboratory work, data integrity and documentation.
- Ability to manage competing priorities and adapt to changing study requirements.
Why Pharmaron?
Collaborative Culture: Join an inclusive environment where teamwork and scientific excellence are supported by our “Employees First” and “Clients Centred” values.
Scientific Breadth: Apply your expertise across in vitro, in vivo, clinical, biological and environmental programmes.
Technical Influence: Shape analytical strategies and solve complex MetID challenges.
Client Visibility: Contribute directly to client discussions, technical updates and study conclusions.
Career Development: Collaborate with specialists across Pharmaron’s global network and help develop our MetID and biotransformation capabilities.
Meaningful Impact: Apply your expertise to programmes supporting new medicines and robust regulatory submissions.