Job Introduction
Position: Senior Scientist I – Metabolite Identification (AMS)
Location: Hoddesdon, UK
Pharmaron is a global CRO helping pharmaceutical and biotechnology companies bring innovative therapies to patients faster. With more than 21,000 employees across 23 sites in the UK, US, and China, we provide fully integrated services spanning drug discovery, development, and manufacturing.
We're proud of the impact we make across the industry. In the last year alone, we supported over 780 discovery projects, 1,000+ CMC programmes, and 1,000+ clinical trials across all phases of development. Our teams work across a broad range of modalities, including small molecules, biologics, and gene therapies, supporting more than 3,000 customers worldwide.
To learn more, visit www.pharmaron.com.
About the Role
We are seeking a Senior Scientist I to join our AMS Metabolism team in Hoddesdon. This is an exciting opportunity for an experienced scientist with expertise in metabolite identification, high-resolution mass spectrometry (HRMS), and LC-MS/MS data interpretation to play a key role in supporting drug development programmes.
Working as a technical specialist within the group, you will lead metabolite identification activities for both regulatory and non-regulatory studies, contribute to scientific discussions with clients, support the development of innovative analytical approaches, and help drive continuous improvement across the department.
Key Responsibilities
- Act as a technical expert in metabolite identification and structure elucidation using High Resolution Mass Spectrometry.
- Conduct analytical and metabolite identification studies to meet project timelines and client requirements.
- Develop and optimise LC-MS/MS chromatographic methods and provide scientific consultation across the wider Metabolism Department.
- Interpret complex analytical data and prepare accurate scientific updates, reports, and study documentation.
- Support client interactions, including scientific discussions, meetings, teleconferences, and site visits.
- Provide technical updates to Project Managers, Study Directors, and senior management throughout the study lifecycle.
- Ensure all work is performed and documented in accordance with GxP requirements, study plans, SOPs, and company standards.
- Maintain responsibility for assigned laboratory equipment, software platforms, and laboratory areas.
- Lead process improvement initiatives and support the development of new services and capabilities within the department.
- Contribute to the external scientific profile of the team through publications, presentations, posters, and participation in expert groups.
- Develop and deliver training materials while mentoring and supporting less experienced colleagues.
- Support project costing activities and provide technical input for bespoke client programmes.
- Participate in recruitment activities, including interviewing and assessing prospective candidates.
Candidate Profile
- PhD, MSc or BSc (Hons) in Chemistry, Biochemistry, or a related scientific discipline.
- Demonstrated experience in metabolite identification within a CRO, pharmaceutical, or agrochemical environment.
- Strong experience in chromatographic method development and optimisation.
- Experience working within regulated GxP environments.
- Proficient in the use of high-resolution mass spectrometry platforms such as Waters Vion, Thermo Q Exactive, and Orbitrap systems.
- Experience using relevant software packages including Xcalibur, Waters UNIFI, and Compound Discoverer.
- Strong understanding of drug metabolism and metabolic pathways.
- Excellent LC-MS/MS data interpretation and structure elucidation skills.
- Strong scientific reporting, presentation, and communication skills.
- Experience coaching, mentoring, and developing colleagues.
- Good project management, organisational, and problem-solving abilities.
- Proficient with Microsoft Office applications.
- Ability to prioritise effectively and manage multiple projects in a fast-paced environment.
Why Pharmaron?
Collaborative Culture: Thrive in an inclusive and innovative environment where teamwork and scientific excellence go hand in hand. At Pharmaron, our core values of "Employees First" and "Clients Centered" shape everything we do.
Meaningful Impact: Join a global organisation supporting world-leading pharmaceutical and biotechnology companies in the development of life-changing medicines.
Career Development: Work alongside industry experts, contribute to cutting-edge science, and benefit from excellent opportunities for professional growth within a truly global organisation.
How to Apply
Ready to take the next step in your scientific career? Join Pharmaron and become part of a team delivering exceptional science and innovative solutions to customers around the world.